Precision Medicine: One size does not fit all.

Genomic Testing: State of the Art

“Trial & Error” = Too Many Trials and Too Many Errors!

Genetically informed treatment strategies = Faster, more efficient, more effective, and safer outcomes.

TWO TYPES OF GENOMIC TESTING both using a simple cheek swab can inform BOTH

Pharmacologic and Complementary Alternative treatment decisions.

Mindful DNA

Mindful DNA is a genetic test used by clinicians that helps guide lifestyle, diet and/or nutritional supplement decisions to improve the overall health and wellbeing of patients based on brain health and the importance of the mind-body connection. The test analyzes 32 genes in six key areas, or domains, of health: Cognition & Mental Acuity, Cardiometabolic, GI & Immune, Stress & Emotional Wellbeing, Inflammation, and Sleep.

For each at-risk gene result, the test report specifies holistic steps patients can take in collaboration with their healthcare provider to achieve better health. The results report provides personalized, actionable information that helps patients adjust their lifestyle, habits and activities in order to improve their quality of life.

Pharmacogenomics

“Better living through chemistry”.

Even though medications for depression, anxiety, ADHD, and mood disorders have been prescribed for several generations, until recently the process of choosing which medication for which person and at what dose has been largely “trial and error”.

Pharmacogenomic testing is designed to use the genetic map of each individual to design a unique treatment plan that will optimize positive results and minimize adverse events.

Genetics

The sequence of DNA that is inherited

•A, T, C, G

•Non-dynamic (aquired mutations are likely deleterious)

Epigenetics

The process of determining if a given gene is expressed

•Histone acetylation, DNA methylation, miRNAs, lncRNA

•Dynamic process à differention and adaptation

ØDriven by elegant biomolecular mechanisms

Impacted by environment